Serum methylprednisolone levels following intra-articular injection of methylprednisolone acetate.

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منابع مشابه

Compared Efficacy of Intra-articular Injection of Methylprednisolone and Triamcinolone

OBJECTIVE To compare the effect of two different corticosteroid types in bilateral and symmetrical knee osteoarthritis (OA). METHODS One hundred and twenty-six patients received injections of methylprednisolone acetate (MP) in one knee and triamcinolone hexacetonide (TH) in the contralateral knee. Patients were evaluated before injection and 2, 4, 8, 12, and 24 weeks after. RESULTS Mean pat...

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Evaluation of intra-articular injection of bupivacaine in combination with morphine, methylprednisolone, or alone on pain after knee arthroscopy

Background and Aims: Knee arthroscopy is used to diagnose and treat intra-articular lesions. The control of acute pain after arthroscopy requires the use of a method with the least side effects and most efficacies. This study aimed to compare the sedative effect of bupivacaine in combination with morphine, methylprednisolone, or alone in knee arthroscopy after intra-articular injection. Materi...

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Disposition of methylprednisolone acetate in plasma, urine, and synovial fluid following intra-articular administration to exercised thoroughbred horses.

Methylprednisolone acetate (MPA) is commonly administered to performance horses, and therefore, establishing appropriate withdrawal times prior to performance is critical. The objectives of this study were to describe the plasma pharmacokinetics of MPA and time-related urine and synovial fluid concentrations following intra-articular administration to sixteen racing fit adult Thoroughbred horse...

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Rectal and oral absorption of methylprednisolone acetate.

Rectal absorption of methylprednisolone acetate and oral absorption of methylprednisolone and methylprednisolone acetate were investigated in a single-dose 3-way crossover study of 12 normal male volunteers. The median value of bioavailability (relative to oral dose) of methylprednisolone acetate based on unchanged methylprednisolone plasma levels was 14.2% after rectal administration, suggesti...

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Herpes zoster following intra-articular corticosteroid injection.

Localized herpes zoster following intra-articular corticosteroid injection is remarkable. We describe an 80-year-old woman with severe osteoarthritis that received an intra-articular injection of 80 mg methylprednisolone in her knee, followed 1 day later by the appearance of linear unilateral vesicles and bullae on her leg in a dermatomal distribution adjacent to the injection site. The roofs o...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 1981

ISSN: 0003-4967

DOI: 10.1136/ard.40.6.571